Respiratory Medicine
We have a breadth of respiratory research within the School of Medicine in terms of conditions, research skills and opportunities.
Respiratory Research is part of the Translational Medical Sciences (TMS) academic unit with sites at City Hospital campus, ÀÖ²¥´«Ã½, (clinical translational, epidemiology and CTIMPs), the Biodiscovery Institute, University Park (basic science) and Queens Medical Centre (clinical translational and CTIMPS). The respiratory theme of the NIHR ÀÖ²¥´«Ã½ Biomedical Research Centre (BRC) facilitates a lot of the respiratory research.
We can provide training across basic science, mechanistic, clinical translational, clinical trials, complex interventions and epidemiology), with university clinical academic PIs focusing on airways disease (COPD and asthma), rare diseases (including LAM), parenchymal lung disease (including LAM and ILD), lung cancer, acute and chronic infection, cystic fibrosis, global health, lung health linked to premature birth and multimorbidity.
For clinical academics, clinical training is usually delivered at ÀÖ²¥´«Ã½ University Hospitals Trust, Sherwood Forest Hospitals Trust (Mansfield) and the Royal Derby Hospital. There are strengths in asthma, COPD, lung cancer, infection, cystic fibrosis and bronchiectasis, interstitial lung disease (ILD)including hosting the national lymphangioleiomatosis (LAM) Centre, pleural disease, ventilation and thromboembolic disease. There are opportunities to train within critical care and respiratory support centres.
There are active links with colleagues within Epidemiology, respiratory paediatrics, Sir Peter Mansfield Imaging Centre, David Greenfield Human Physiology Unit, digital health and bioinformatics.
We have a strong track record of training in respiratory clinical academia – at foundation level as well as Academic Clinical Fellows, Clinical Research Fellows and Clinical Lecturers. Many have gone on to become research leads and senior clinical academics.
Academic Clinical Lecturers
Frances Grudzinska
Frances is an academic clinical lecturer in Respiratory Medicine. Frances was awarded a PhD investigating factors influencing outcomes for older adults with community acquired pneumonia.
Frances’ research interest is community-acquired pneumonia. Her research spans the immunological deficits seen in pneumonia, understanding patient priorities and outcome measures through to establishing who is at risk of adverse outcome following CAP.
For more information about Frances's research, please see .
Frances Grudzinska
Ayushman Gupta
"I am an ST6 Respiratory registrar currently working as a clinical lecturer in ÀÖ²¥´«Ã½ since August 2024. My previous research experience includes a PhD in assessing multi-organ physiological sequelae of severe COVID-19 in the long-term. I utilised novel functional MRI techniques during simultaneous supine exercise, in order to understand mechanisms of persistent fatigue.
"My current research interests include experimental medicine focusing on COPD and recovery from acute respiratory illnesses with applied functional MR imaging. For my clinical lectureship, I aim to build on my PhD work and incorporate the in-bore exercise protocol with other imaging modalities, to stress the body and assess changes in physiology in different organs and clinical states.
"At present I am conducting feasibility of the exercise protocol with functional lung MRI in healthy volunteers to assess regional changes in ventilation. I aim to use this as proof of principal to study regional ventilatory response to exercise in patients with stable COPD to better understand mechanisms of exertional dyspnoea. I hope this will form the basis for application to an advanced fellowship whereby exercise induced ventilatory changes can be assessed following specific interventions, e.g. lung volume reduction, to further improve clinical effectiveness. "
For more information about Ayushman's research, please see .
Ayushman Gupta
Find out more
More information about Respiratory Research at the ÀÖ²¥´«Ã½
For more information about Professor Charlotte Bolton and to contact her for queries about ACF and CL research opportunities, please visit her staff profile on the School of Medicine website.