SPMIC Research Staff
Dr Stephania Assimopoulos
In my work I focus on diffusion MRI and tractography, as well as developing methods for mapping brain (dys)connectivity in health and disease. I have also developed novel techniques for mapping homologous brain regions across species, as well as making significant contributions to the widely used neuroimaging package FSL XTRACT. Most recently I have extended into preclinical (mouse) MRI and integration with light-sheet microscopy data.
show/hide full profile...
Dr Michael Asghar
I am a post-doctoral researcher specialising in high-resolution, high-field functional MRI. I completed my PhD in 2019, during which I used population receptive field models to map the somatosensory cortex, following a scan involving multiple finger stimulation.
show/hide full profile...
My current work involves 3T imaging, where we are looking at measuring brain-csf-barrier permeability non-invasively in patients with inflammatory bowel disease. We are also finishing a MEG-7T study which looked at patients with focal hand dystonia. Finally, a new project involves activating noci-responsive area 3a, an area of the brain that responds preferentially to painful stimuli.
Dr Chris Bradley
I’m an MRI physicist and researcher specialising in the development, optimisation, and clinical translation of advanced MRI protocols for whole-body and multi-organ imaging, including abdominal, cardiac, and musculoskeletal applications. My work focuses on quantitative, multi-parametric, and multi-nuclear MRI to assess tissue structure, function, and metabolism across the lifespan, including measurements of fat content, iron content, inflammation and fibrosis. Based at the Sir Peter Mansfield Imaging Centre, I design, harmonise, and validate MRI protocols across Philips, Siemens, and GE platforms.
show/hide full profile...
This work bridges research and clinical imaging, ensuring advanced MRI methods are robust, reproducible, and suitable for real-world deployment in both healthcare. While much of my research has focused on liver and metabolic disease, my expertise extends to MR elastography, spectroscopy, and whole-body MRI, enabling comprehensive, non-invasive assessment of organ health. I am particularly interested in the role of quantitative MRI in health screening and precision imaging for clinical interventions. In addition to my research role, I am an MRI Scanner Operator with responsibility for participant and researcher safety across both Sir Peter Mansfield Imaging Centre sites. I support imaging on Philips 3T, and 7T systems, a GE 3T system, and am working towards competency on Siemens Sola 1.5T scanners. I also train post-doctoral researchers and PhD students in MRI operation and protocol optimisation, ensuring high-quality, reproducible data acquisition while prioritising participant comfort and safety.
Dr Charlotte Buchanan
My research involves the use of multiparametric Magnetic Resonance Imaging (MRI) in healthy individuals and people with Chronic Kidney Disease (CKD) to understand how the kidneys function and change with disease. I have a particular interest in developing MRI protocols across sites for large cohort studies and harmonising these protocols across the three MR vendors.
show/hide full profile...
Dr Haiwei Chen
My research focuses on the development of advanced radiofrequency (RF) engineering technologies for ultra-high-field magnetic resonance imaging (MRI), with particular emphasis on RF coil design, electromagnetic field manipulation, and safety management for next-generation human imaging at 7 T and 11.7 T. I combine electromagnetic simulation, hardware development, and experimental validation to improve RF field uniformity, transmission efficiency, and patient safety in UHF MRI systems.
show/hide full profile...
Much of my work centres on the design of innovative multi-channel transmit/receive RF coil arrays and the use of artificial electromagnetic materials, including metamaterials and high-permittivity components, to control RF field distributions. I also develop methods for specific absorption rate (SAR) evaluation, B1+ shimming optimisation, and model-based prediction of RF performance. These approaches aim to address longstanding technical challenges in ultra-high-field imaging, such as non-uniform excitation, elevated local SAR, and reduced efficiency of conventional coil architectures.
More recently, my research has expanded to support the development of RF technologies for the 11.7 T whole-body human MRI system. This includes RF coil development, RF safety assessment, coil–scanner interface engineering, and validation frameworks for future parallel-transmission and multi-nuclear imaging. I collaborate widely with academic and industrial partners, with the overarching aim of enabling the next generation of high-performance UHF MRI for neuroscience, clinical research, and biomedical applications.
Dr Daniel Cocking
I am a post-doctoral researcher focusing on developing new ways to use 1H and 2H magnetic resonance spectroscopy (MRS) to investigate how neurochemical concentrations vary functionally in neurological conditions as well as in pathological diseases. Whilst my research mostly relies on the use of our 7T scanner, I also aim to implement these strategies on the 11.7T scanner.
show/hide full profile...
Dr Eleanor Cox
My research focuses on using multi-organ body magnetic resonance imaging (MRI) to understand how abdominal organs function and respond in diseases such as chronic kidney disease, acute kidney injury, liver cirrhosis. Techniques include assessment of blood flow, perfusion, microstructure and organ structure. In addition, I work on a liver cancer surveillance trial which aims to improve the detection of liver cancer in high-risk patients using MRI. I have extensive experience in analysis of multicentre trials and large datasets, including the UK Biobank.
show/hide full profile...
Dr Alex Daniel
My research focuses on increasing the availability of renal transplant donations. A large number of potentially viable kidney donations are discarded due to a lack of confidence that the organ is sufficiently healthy to be transplanted into a recipient. By assessing the viability of potentially usable organs using ex-vivo renal MRI we aim to increase the use of these marginal organs. Additionally I work on the development of software tools for the analysis renal MRI including artificial intelligence and standardisation of processing pipelines.
show/hide full profile...
Dr Rebecca Dewey
I use MRI and other imaging modalities such as electrophysiological measures to improve our understanding of hearing and deafness. MRI can help us see damage to the hearing system and nerves that result from aging and noise exposure. New technological advancements can help us improve how people with hearing difficulties receive treatment.
show/hide full profile...
Dr Neele Dellschaft
I am working at the Sir Peter Mansfield Imaging Centre on a number of projects including digestive health (in people with irritable bowel syndrome, IBS, and in neonates).
show/hide full profile...
These projects allow me to apply my previous knowledge in physiology (perinatal health, longterm metabolic health, nutrition) using MRI.
Dr Sally Eldeghaidy
My research involves the development and application of brain imaging techniques, focusing on understanding food-related brain perception and interactions between the brain and gut (brain-gut axis) in healthy and clinical cohorts. This includes investigating the brain's perception to taste, aroma, flavour and oral fat emulsions; the physiological mechanism involved in satiation through brain-gut interactions; and the effect of taste phenotype and genotype on food perception, preference and choice.
show/hide full profile...
Dr Alicia Falcon Caro
My main research focus is on the application of low-intensity focused ultrasound stimulation (FUS) to improve brain and mental health. I use MRI and electrophysiological sensors, such as electroencephalography (EEG), to help us understand the physiological mechanism of FUS. At the moment, I am developing a closed-loop transcranial FUS system that aims to provide a more personalised and effective neuromodulation treatment.
show/hide full profile...
Dr Yang Gao
My research explores how electromagnetic wave propagation can be engineered to transform ultra-high-field magnetic resonance imaging (MRI). I develop new RF transmission architectures that improve imaging efficiency, robustness, and safety, with the goal of enabling simpler and more accessible MRI systems
show/hide full profile...
Dr Lauren Gascoyne
My main research focus is on the clinical application of magnetoencephalography, investigating abnormal brain function in a variety of patient populations. I also use novel optically-pumped magnetometer technology to investigate muscle and foetal signals. Currently, I am also involved in a number of gastro-intestinal MRI projects focusing on Crohn's disease and the relationship between the gut and brain.
show/hide full profile...
Dr Ryan Hill
show/hide full profile...
Dr Caroline Hoad
I have worked at the SPMIC for 21 years with my research focus on MRI sequence development and image analysis techniques for abdominal imaging. In particular I have an interest in using MRI to assess motility throughout the gastrointestinal (GI) tract. I also work on quantitative imaging of the abdomen including relaxometry with applications in functional GI diseases, Inflammatory Bowel Disease and Cystic Fibrosis.
show/hide full profile...
Dr Akshay Kumar
Dr. Akshay Kumar is Senior Research Fellow and Facility Manager of the DNP MAS NMR facility at Sir peter Mansfield Imaging Center at the ÀÖ²¥´«Ã½. He develops and applies dynamic nuclear polarization (DNP)-enhanced solid-state NMR to reveal the atomic-scale structures of materials that remain inaccessible to conventional techniques. His research spans from the molecular architecture of native plant cell walls to the chemistry of high-performance polymers, advancing both fundamental science and sustainable technologies.
show/hide full profile...
Dr. Kumar earned his PhD at Université Grenoble Alpes, France under the supervision of Dr. Gaël De Paëpe and Dr. Sabine Hediger, where he pioneered DNP methods that provided unprecedented insight into biopolymer structures. He then joined Radboud University Nijmegen in the Netherlands as a postdoctoral researcher with Prof. Arno Kentgens, extending these approaches to synthetic polymers and leading projects on large-scale recycling. He has collaborated with world leading companies such as DSM, Teijin Aramids and KINGFA, and academic groups of leading groups including Prof. Ben Feringa at Univ. Of Groningen, while funded by Dutch Polymer Institute Eindhoven. He has published his work in leading international journals, including Polymer, Chemical Science, and RSC Green Chemistry. At ÀÖ²¥´«Ã½, Dr. Kumar manages the DNP MAS NMR platform, enabling collaborations across chemistry, physics, and materials science, while continuing his research to push the boundaries of molecular-level characterization for materials of the future.
Dr Niall Holmes
show/hide full profile...
Dr James Leggett
show/hide full profile...
Dr Olivier Mougin
My research involves development and application of quantitative MR imaging, focusing particularly on physical properties such as Chemical Exchange Sarutation Transfer (CEST) and longitudinal relaxation time (T1) at ultra high field (e.g. 7T) in the brain, but also in the body (both 3T and 7T). I am also interested in motion mitigation processes for MRI at all fields, using retrospective algorithms as well as prospective correction methods. I am also working on realising the potential of Open MRI focusing on the reconstruction pipeline to improve the speed and quality of imaging using the ASG Paramed 0.5T upright system.
show/hide full profile...
Dr Rosemary Nicholas
My research involves using MRI to assess the impact of physical activity (or inactivity) on the structure and function of the body as we age. My current focus is on the ongoing Concurrent multi-organ responses to chronic physical activity and inactivity (CHAIN) study investigating the impact of increasing or decreasing physical activity over a period of 6 months in a middle-aged group of volunteers. We assesses body composition through fat and muscle distribution, the health of the liver and kidneys as well as the structure and functional quality of the brain, heart and skeletal muscle at rest and during exercise inside the MR bore.
show/hide full profile...
Dr Zachary Peggs
My research focuses on the development and validation of quantitative MRI methods for assessing lung structure and function. I have a particular interest in free-breathing approaches for measuring regional ventilation and perfusion, including the development and application of VOLVE MRI. My broader research interests include image reconstruction, non-rigid registration, oxygen-enhanced MRI, physiological modelling and MRI during exercise. Across these areas, I aim to develop robust and sensitive methods that can be applied widely in respiratory research and to the study of pulmonary physiology.
show/hide full profile...
Dr Ben Prestwich
My research focuses on mapping sodium in the body using sodium MRI. During my PhD, I helped set up sodium MRI at the Sir Peter Mansfield Imaging Centre, which involved installing custom-built equipment and developing new scanning methods. My early work focused on imaging the kidneys, as well as the skin and muscles in the leg. Since then, I’ve been using these techniques to explore how sodium levels change in different conditions. This includes studying people with end‑stage kidney disease who receive dialysis, and looking at how sodium in muscles is affected by exercise. More recently, we have also adapted these methods to scan the brain, where sodium MRI is helping us understand brain tumours in new ways.
show/hide full profile...
Dr Abi Spicer
I use both Magnetic Resonance Imaging (MRI) and Spectroscopy (MRS) to study the body at 3T. My PhD focussed on using MRI and MRS to look at the liver in health and disease. I have worked extensively optimising and using multinuclear MRS (13C and 31P) to look at the liver in both healthy populations and patients with type 2 diabetes undergoing weight-loss surgery. My current work focuses on MRI (with a small amount of MRS sprinkled in) of the digestive tract. We have imaged all the way from the oesophagus to the rectum to look at the effects of different treatments in healthy volunteers as well as patients with IBS and cystic fibrosis.
show/hide full profile...
Dr Shaun Warrington
My primary research interest is in establishing robust methods for estimating structural brain connectivity across species and individuals, and using these features to reveal links between structural connectivity and behaviour/cognition in evolution, development and disease. My current focus is on high resolution ultra high field diffusion MRI (10.5 T) in the non-human primate brain. I am the lead developer of the open-source tool XTRACT for the automated and standardised estimation of major white matter fibre bundles in the human (neonate and adult) and non-human primate brain using diffusion tractography. I also curated ON-Harmony, an open and comprehensive multi-modal MRI travelling-heads harmonisation resource which includes UK Biobank scanners.
show/hide full profile...